It's a pain. Well, it can be. You take off the intake piping, fan blade, fan shroud, power steering pump, then you get to take off the water pump (Which if you have the same engine as me in my S10, is pretty much the entire front of the engine). These bolts are shallow, and very easy to strip. If you're lucky enough to get that out, then you start taking off the intake, exhaust manifolds (Which the bolts also always rust and like to snap). There's a lot more to it, but that's the only areas I've ever heard of someone running into.
1999 Chevrolet Camaro SS (PC'd)
1994 Chevrolet Beretta Z26 Q4 (W41 M90'd)
2004 Chevrolet Silverado 2500 (4WD)
My wife's cars:
1971 Dodge Charger SE (stock and original 383 auto)
2004 Subaru Impreza WRX (kid-hauler)